Octavia Spencer

~ as ~

Madam C. J. Walker

Tiffany Haddish

~ as ~

Lelia

Carmen Ejogo

~ as ~

Addie

Garrett Morris

~ as ~

Cleophus Walker

Kevin Carroll

~ as ~

Ransom

J. Alphonse Nicholson

~ as ~

John Robinson

Blair Underwood

~ as ~

Charles James Walker

Karen Glave

~ as ~

Peggie Prosser

Mouna Traoré

~ as ~

Esther

Chris Tarpos

~ as ~

Townsman (uncredited)