Ronald Colman

~ as ~

Dr. Martin Arrowsmith

Helen Hayes

~ as ~

Leora Tozer Arrowsmith

Richard Bennett

~ as ~

Gustav Sondelius

A.E. Anson

~ as ~

Professor Max Gottlieb

Clarence Brooks

~ as ~

Dr. Oliver Marchand

Alec B. Francis

~ as ~

Twyford

Claude King

~ as ~

Dr. Tubbs

Bert Roach

~ as ~

Bert Tozer

Myrna Loy

~ as ~

Joyce Lanyon

Russell Hopton

~ as ~

Terry Wickett