Jenifer Lewis

~ as ~

Jackie Washington

Tim Curry

~ as ~

Edward Whatsett St. John

T.V. Blake

~ as ~

Antandra Washington (Jackie's Daughter)

Tangie Ambrose

~ as ~

Shaniqua Summers Wells (Jackie's Daughter)

Whoopi Goldberg

~ as ~

Nurse Ethyl Washington Rue Owens (Jackie's Sister)

Robert Bailey Jr.

~ as ~

Wilson Wells (Jackie's Grandson)

Tom Arnold

~ as ~

Marvin Pritz (Jackie's Former Manager)

Loretta Devine

~ as ~

Snookie Tate (Jackie's Childhood Friend)

Julie Hagerty

~ as ~

Pammy Dunbar (Infomercial Host)

David Hyde Pierce

~ as ~

Perry (The Deaf Rehearsal Pianist)